Coated tablets: Box of 300

COMPOSITION: Each coated tablet contains Paracetamol 500 mg, Excipients.

INDICATIONS: Paracetamol is an effective analgesic and antipyretic for the control of mild or moderate pain caused by joint disorders, ear pain, headaches, odontogenic pain, neuralgia, minor surgical procedures, etc.

It is also effective for the treatment of fever such as that caused by viral infections, post-vaccination fever, etc.

DOSE: Adults: The usual dose for analgesia and fever control is 325 to 1,000 mg every four hours, up to a maximum of 4 grams per day.

In patients with renal insufficiency, it is recommended to increase the administration interval to six hours, as in patients with moderate renal damage, and to eight hours in patients whose glomerular filtration rate is less than 10ml/min.

In case of hepatic insufficiency, 2g/24 hours will not be exceeded and the minimum interval between doses will be 8 hours.

Pregnancy and Lactation: Corresponds to pregnancy risk category B, its non-prolonged use is considered safe during the three trimesters of pregnancy.

It is compatible with lactation.

CONTRAINDICATIONS and PRECAUTIONS:

Hypersensitivity to acetaminophen, because it is metabolized in the liver, it should be administered with caution in patients with liver damage, as well as in those who are receiving hepatotoxic drugs or who have some type of nephropathy.

The risk of hepatotoxicity is rather high in patients with alcohol dependence and in patients receiving more than one medication containing acetaminophen.

Avoid the use of high doses in patients with hepatic dysfunction.

Avoid use in patients with phenylketonuria or G6PD deficiency.

Use with caution in patients with dehydration or chronic malnutrition. Self-medication with paracetamol should be limited when being treated with anticonvulsants, since it enhances hepatoxicity and decreases the bioavailability of paracetamol.