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THERAPEUTIC CLASSIFICATION:

Anti-glaucoma and miotic preparations, beta-blocking agents: timolol

 

COMPOSITION

TIMOLOL MALEATE (Equivalent to Timolol base 5 mg) 6.83 mg per mL of solution

SOLUTION

 

USES AND ADMINISTRATION

Non-selective β-blocker without significant direct cardiac stimulant or depressant activity or local anesthetic activity.

 

INDICATIONS:

Reduction of elevated intraocular pressure in patients with open-angle glaucoma and ocular hypertension. Patients with intolerance to other drugs that decrease intraocular pressure.

 

HOW TO USE:

Ophthalmic route Eye instillation according to medical prescription. Usual dose in adults: 1 drop of ophthalmic solution per day in each affected eye, preferably during the first hours of the morning. In case of using more than one topical ophthalmic medication, they should be applied with a lapse of at least 5 minutes between them.

 

CONTRAINDICATIONS:

Known hypersensitivity to the active ingredients or to the derivatives of the prostaglandins. Contraindicated in pregnancy and lactation; aphakia and pseudoafaquia, macular edema, cystoid macular edema. Hypersensitivity to benzalkonium chloride and beta blockers. Patients with asthma or severe atrio-ventricular block, as well as in heart failure.

 

ADVERSE EFFECTS:

In general, it is well tolerated. Occasionally, pigmentation has occurred in the iris. The most frequently reported side effect, for this association, is burning in the application and conjunctival hyperemia, foreign body sensation and local irritation that does not prevent it from being applied.