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Corticosteroids and anti-infectives in association, ophthalmic use



TOBRAMYCIN / DEXAMETHASONE 3 mg / 1 mg per 1 g of ointment




DEXATOBRIN Ophthalmic Ointment is an association of: corticosteroid inhibitor of inflammatory response and bactericidal aminoglycoside antibiotic component, powerful, broad spectrum, which acts on bacterial cells by inhibiting the synthesis and binding of polypeptides on the ribosome.


Dexamethasone + tobramycin in ophthalmic ointment is indicated in the inflammatory process of the anterior segment of the eye, associated with superficial bacterial infection or with risk of said infection.


The usual dose for mild or moderate infections is approximately 1 cm of ointment in the affected eye / s two or three times a day. In severe infections, the dose is approximately 1 cm of ointment in the affected eye / s every three or four hours until the improvement is noticed, continuing with a more reduced treatment until the indicated treatment period is completed.

Follow these instructions unless your doctor has given you different indications.

Children: can be used in children, from one year of age, at the same dose as in adults. Remember to apply your medication when appropriate.

Your doctor will tell you the duration of your treatment. Do not stop the treatment sooner unless your doctor tells you to.



Risk of masking acute purulent ocular infection. Perforation has been described in cases that involve thinning of the cornea and sclera. Frequent monitoring of IOP is recommended. Consider a possible fungal infection in persistent ulceration of the cornea, when steroids are used or have been used. With prolonged use risk of: ocular hypertension / glaucoma, optic nerve injury, alteration of acuity and visual field, formation of posterior subcapsular cataract, ocular infection. Not recommended in children <1 year.

“Contraindicated in pregnancy or when its existence is supposed”



The most frequent adverse effects were itching, redness of the eye and lacrimation. Other adverse effects that can be experienced in the eyes are discomfort and symptoms of allergic reactions such as secretions, swelling of the conjunctiva and eyelids and redness of the eyelids.

You can usually continue using the ointment, unless the effects are severe. If in doubt, consult your doctor or pharmacist