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THERAPEUTIC CLASSIFICATION:

Anti-arthritis Anti-inflammatory

 

COMPOSITION

Meloxicam 15mg

Glucosamine sulfate 1500mg

Granules for oral solution

 

COMPOSITION:

Each 4g sachet of granules for oral solution contains:

Meloxicam …………………………………………. ….. 15 mg

Glucosamine Sulfate Potassium Chloride …… 1990 mg

(Equivalent to 1500 mg of Glucosamine Sulfate)

 

USES AND ADMINISTRATION

The pharmacological properties of glucosamine sulphate explain its beneficial activity in the degenerative and dismetabolic processes of osteoarthritis and in particular on the symptoms of the disease in different locations.

The administration of glucosamine sulfate allows to supplement the endogenous deficiencies of this substance, thus stimulating the biosynthesis and inhibiting the degradation of the proteoglycans, necessary to achieve a trophic effect in the articular facets, favor the fixation of sulfur in the synthesis of chondroitin sulphuric acid and facilitate the normal deposit of calcium in the bone tissue.

Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) belonging to the group of enolcarboxamides. By inhibiting cyclooxygenase, locally prevents the conversion of arachidonic acid into cyclic endoperoxides, which are transformed into prostaglandins, thromboxanes and inflammation mediators circulating autacoids and eicosanoids. By inhibiting cyclooxygenase and the subsequent synthesis of prostaglandins, the release of proinflammatory substances and mediators is reduced, preventing the activation of the terminal nociceptors.

The chondroprotective and repairing effect of glucosamine, combined with the analgesic and anti-inflammatory action of meloxicam, significantly alleviates pain at rest and movement, improving mobility in the short and medium term.

 

INDICATIONS:

Symptomatic treatment of osteoarthritis (osteoarthrosis – osteoarthritis) and other articular and extra-articular rheumatic diseases.

HOW TO USE:

In a glass of boiled and cold water, pour the contents of an envelope, shake and drink once a day, preferably with breakfast

 

CONTRAINDICATIONS:

• Hypersensitivity to any of the formula’s components.

• Severe hypersensitivity to other NSAIDs.

• Phenylketonuria.

 

“Contraindicated in pregnancy or when its existence is supposed”

“Contraindicated in cases of gastritis, ulcers and / or gastroduodenal hemorrhages”

 

ADVERSE EFFECTS:

Meloxicam:

• Gastrointestinal: Occasionally: dyspepsia, nausea, vomiting, abdominal pain,

constipation, flatulence and diarrhea. Rarely: transient alteration of liver function parameters, (hepatic enzymes, increased bilirubin), belching, esophagitis, gastroduodenal ulcer, occult or macroscopic gastrointestinal bleeding.

• Glucosamine sulfate:

The side effects of glucosamine sulfate are uncommon and generally of a mild and transient nature. On rare occasions, the onset of nausea, heaviness, abdominal pain, bloating, constipation, diarrhea, dizziness, drowsiness and headache has been described. Hypersensitivity reactions: erythema, pruritus or bronchial asthma have been reported with low incidence